Friday, February 24, 2017

St. Jude Researchers Discover Important Bacterial Mutation


Philip Bowman leads Peerless Surgical, a leading distributor of Arthrex surgical products in South Carolina and Western North Carolina. In addition to his professional responsibilities at Peerless Surgical, Philip Bowman supports pediatric patients through contributions to St. Jude Children's Research Hospital. 

St. Jude Children's Research Hospital is the nation's leader in understanding childhood cancer and other diseases that impact pediatric patients. Through research efforts and ongoing advocacy, St. Jude has helped raise the childhood cancer survival rate to more than 80 percent over the last 50 years. 

St. Jude researchers recently discovered a mutation that makes bacteria resistant to some antibiotic therapies. This discovery came about as a result of one patient, an infant who was receiving medical care for acute myeloid leukemia. The infant patient was experiencing a prolonged blood stream infection, which developed and persisted despite strict precautions.

While sequencing DNA samples taken from the patient, researchers learned of a point mutation in the relA gene of the vancomycin-resistant Enterococcus faecium the patient had contracted. The patient has since recovered, and researchers now have a new understanding of potential therapies for this type of resistant bacteria.